Updated dailyPubMed-sourced · Research, not medical advice
← Peptide GuidesMuscle & Performance

IGF-1 LR3

Also known as: IGF-1 LR3 · Long R3 IGF-1

A modified, long-acting form of IGF-1 used in research and misused in sport.

⚕️ Educational reference only — not medical advice. Many peptides are not approved for human use and are sold for research purposes only. Always consult a qualified healthcare professional.

Overview

IGF-1 LR3 is a chemically modified, longer-acting version of insulin-like growth factor 1 (IGF-1), used as a cell-culture research reagent and misused for muscle growth.

How It's Thought to Work

IGF-1 drives cell growth and proliferation; the LR3 modification extends its half-life and reduces binding to carrier proteins, increasing activity.

What the Research Says

Used legitimately as a laboratory reagent; there is no approved human therapeutic use of IGF-1 LR3, and human safety data for that use is lacking.

Regulatory & Legal Status

Not FDA-approved for human use. A research reagent; prohibited in sport by WADA.

Safety Considerations

Potentially serious risks (e.g., hypoglycemia, effects on growth of tissues). No approved human use. Consult a qualified clinician.

Frequently Asked Questions

What is IGF-1 LR3?

IGF-1 LR3 is a chemically modified, longer-acting version of insulin-like growth factor 1 (IGF-1), used as a cell-culture research reagent and misused for muscle growth.

How does IGF-1 LR3 work?

IGF-1 drives cell growth and proliferation; the LR3 modification extends its half-life and reduces binding to carrier proteins, increasing activity.

What does the research say about IGF-1 LR3?

Used legitimately as a laboratory reagent; there is no approved human therapeutic use of IGF-1 LR3, and human safety data for that use is lacking.

Is IGF-1 LR3 FDA-approved or legal to buy?

Not FDA-approved for human use. A research reagent; prohibited in sport by WADA.

Is IGF-1 LR3 safe? What are the risks?

Potentially serious risks (e.g., hypoglycemia, effects on growth of tissues). No approved human use. Consult a qualified clinician.

On the Podcasts

  • Peptide Q&A #58 – Shelf Life, Drug Test, HGH vs IGF-1 LR3 & Carnivore Diet
  • Peptide Q&A #51 – HGH vs IGF-1 LR3, Wolverine for Dogs, GHRH & GHRP Explained & Low Libido on TRT
  • Peptide Q&A #39 – The Full GH Peptide Breakdown, IGF-1 LR3 Protocols, with Paul Bakhtiar

Want the latest on IGF-1 LR3 as it publishes?