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PT-141

Also known as: PT-141 · Bremelanotide · Vyleesi

A melanocortin peptide; an approved version treats certain sexual-desire disorders.

⚕️ Educational reference only — not medical advice. Many peptides are not approved for human use and are sold for research purposes only. Always consult a qualified healthcare professional.

Overview

PT-141 (bremelanotide) is a melanocortin-receptor agonist. An approved formulation, Vyleesi, is prescribed for hypoactive sexual desire disorder in some premenopausal women.

How It's Thought to Work

Unlike vascular-acting drugs, it acts on melanocortin receptors in the central nervous system that are involved in sexual arousal pathways.

What the Research Says

The approved indication is supported by human clinical trials. 'Research chemical' PT-141 sold online is a separate, unregulated product.

Regulatory & Legal Status

The approved version (Vyleesi) is prescription-only for a specific indication. Gray-market PT-141 is unapproved.

Safety Considerations

Approved use has defined warnings (including blood-pressure effects). Unregulated versions carry added risk. Consult a clinician.

Research Sourcing

Where to source PT-141 for research

Vendors below publish third-party certificates of analysis. For laboratory research use only — not for human consumption.

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Some links below are affiliate links. If you purchase through them, Peptide Research News may earn a commission at no additional cost to you. We only list vendors that publish third-party certificates of analysis (COAs). Listing is not an endorsement for human use — peptides are sold for laboratory research purposes only.

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On the Podcasts

  • Peptide of the Week: KPV & PT-141 – Gut Health, Inflammation & Libido
  • PT-141 Explained and Revisted: The Brain-Based Peptide for Desire, Arousal, and Performance

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